Files

Download

Download Full Text (1013 KB)

Description

Deoxyribonucleic acid (DNA) codes for proteins using a unique order of four major nitrogenous bases adenine, thymine, cytosine, and guanine. In several biological applications, such as the determination of DNA stability, production of biologic based drugs, and even taxonomic reorganization of species, it becomes necessary to understand the relative amounts of each nucleotide in a DNA sample, regardless of their sequence. However, most assays used to determine base composition use expensive equipment, harsh chemicals, and advanced computer software. In addition, the determination of base composition is an important educational tool in undergraduate laboratories, but these limitations are infeasible for many institutions. Therefore, our research focus is to develop an easier, safer, and faster base composition assay.

Publication Date

4-2023

Disciplines

Arts and Humanities | Business | Education | Engineering | Higher Education | Life Sciences | Medicine and Health Sciences | Physical Sciences and Mathematics | Social and Behavioral Sciences

Colorimetric Redox Reactions to Determine Base Composition in Unknown Monomeric DNA Samples

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.