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Description

Capacitive bioparticle detection is a promising method for point-of-care diagnosis. There are a wide range of applications for such a device: diagnostics, pharmacology, and medical science. The end goal of this project is to develop a portable capacitive sensing platform for rapid and sensitive bioparticles detection. When bioparticles bind to receptors located on the surface of the electrode there would be a change in the interfacial capacitance, which indicate the presence of the bioparticle. The ADuCM355 – a precision analog microcontroller with a chemical sensor interface – is being used to perform biased electrochemical impedance spectroscopy (EIS). An AC potential is applied across the electrodes at varying frequencies, and the resulting current is measured and transferred to a master device. The ADuCM355 is controlled via the serial peripheral interface (SPI) by a master device. While multiple microcontrollers are compatible with the ADuCM355, currently a mbed lpc1768 acts as the master device receiving data to be decoded and displayed. In the future multiple sensors can be connected to a single master device and take concurrent readings for more accurate sensing. The main requirements for the device are portability, affordability, and the ability to provide appropriate and adjustable AC signals.

Publication Date

Spring 2021

Disciplines

Arts and Humanities | Business | Education | Engineering | Higher Education | Life Sciences | Medicine and Health Sciences | Physical Sciences and Mathematics | Social and Behavioral Sciences

A Portable Analyzer For Rapid And Sensitive Protein Detection By Ac Electrokinetics Capacitive Sensing

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